Pharmacokinetics of cisplatin and DWA-2114R in experimental animals.

simulation and experimental studies for prediction mineral scale formation in oil field during mixing of injection and formation water

abstract: mineral scaling in oil and gas production equipment is one of the most important problem that occurs while water injection and it has been recognized to be a major operational problem. the incompatibility between injected and formation waters may result in inorganic scale precipitation in the equipment and reservoir and then reduction of oil production rate and water injection rate. ...

Scorpion Venom Pisoning in Experimental Animals

Fasting and Experimental Animals, Detrimental or Positive?

While fasting has been practiced for centuries, its beneficial effects was unknown until recently. This review tries to analyze the current literature of how fasting and intermittent fasting (IF) could affect clinical pathological parameters, learning, mood and brain plasticity. The effects of different ways of fasting on metabolism and stress were also explored. Animal experiments have elucida...

Pharmacokinetics of neothramycin in animals and man.

The pharmacokinetics of neothramycin (NTM) was performed in mice, rabbits and man. Biological half-life of NTM in man after a 20 mg bolus injection produced an alpha phase half-life of 3.63 minutes, a beta phase half-life of 84.5 minutes and a volume of distribution at a steady state of 50.3 liters/body. Its human half-life was longer than those of adriamycin, mitomycin C and neocarzinostatin, ...

Biodistribution analysis of cisplatin in liposomal form in animals with cisplatin-resistant and cisplatin-sensitive carcinoma.

AIM To analyze the relation between pharmacokinetics of cisplatin in liposomal form and antitumor efficacy toward cisplatin-resistant and cisplatin-sensitive variants of Guerin carcinoma. METHODS Concentration of platinum was measured by atomic absorption spectrophotometry (C115M1 "Selmi", Ukraine). Elimination constant was calculated based on the dynamics of cisplatin concentration in time p...